Thymalin 10mg
At molecular level, its short‑peptide components bind to DNA and histone proteins to modulate target‑gene expression in immune‑related cells. It supports the differentiation and maturation of T‑lymphocytes inside the thymus, normalizes CD4/CD8 lymphocyte ratio, enhances NK‑cell activity, and reduces excessive lymphocyte apoptosis.
In pre‑clinical research, Thymalin is mainly studied for thymus‑function restoration, immunosenescence modulation, immune‑balance adjustment, anti‑inflammatory response, and geroprotective mechanisms. Research also covers immune recovery after injury or chemical‑induced immune damage.
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Detail
Peptide Bioregulator · For Laboratory Use Only
Thymalin 10mg
Thymus-Derived Peptide Complex · Immune Research Bioregulator · Lyophilized Powder
Thymalin is a thymus-derived peptide bioregulator — a standardized polypeptide complex obtained from thymus tissue. It belongs to the family of short-peptide bioregulators pioneered by Prof. Vladimir Khavinson and has been one of the most extensively studied immunomodulatory peptide preparations since the 1980s.
Research has identified short peptides such as Glu-Trp, Lys-Glu and Glu-Asp-Pro among its active components, which are believed to act as signal molecules regulating thymus function and T-cell immunity. Each vial is supplied as a sterile lyophilized (freeze-dried) powder to ensure maximum stability.
Product Specifications
Product Name Thymalin (Thymic Peptide Bioregulator) CAS Number 79621-14-0 Nature Thymus-derived polypeptide complex (multi-peptide mixture; no single molecular formula or weight) Key Active Fragments Glu-Trp, Lys-Glu (dipeptides); Glu-Asp-Pro (tripeptide) Quantity 10mg per vial Physical Form White to off-white lyophilized powder Quality Control Batch-tested by HPLC & MS; COA available upon request Storage -20°C for long term; 2–8°C for short term (lyophilized) What is Thymalin?
The thymus is the central organ of the immune system, where T lymphocytes mature and acquire their function. With aging, the thymus gradually involutes and its peptide output declines — a process closely associated with immune aging (immunosenescence).
Thymalin was developed in the Soviet Union by Prof. V.G. Morozov and Prof. V.Kh. Khavinson as a preparation that delivers the thymus's own regulatory peptides. Unlike single-molecule peptides, Thymalin is a physiological peptide complex: a balanced set of short peptides naturally present in thymus tissue, which is thought to restore thymic function in a tissue-specific, self-regulating manner.
Over decades of research, Thymalin has been investigated in a wide range of settings, including:
- Immune dysfunction and immunodeficiency models;
- Recovery of immune status after chemotherapy, radiation and severe infection;
- Tumor models, where antitumor effects were reported in animal experiments;
- Aging research, where it was shown to normalize immune parameters in older subjects.
As one of the flagship compounds of the peptide bioregulator concept, Thymalin remains a key research tool for studying thymus biology, immune regulation and the immunology of aging.
Proposed Mechanism of Action
Handling & Storage Guidelines
- Lyophilized powder: Store at -20°C for long-term stability; 2–8°C is acceptable for short-term storage. Avoid repeated temperature cycling and protect from light.
- Before opening: Allow the vial to reach room temperature and briefly centrifuge to ensure the full contents collect at the bottom of the vial.
- Reconstitution: Add bacteriostatic water or an appropriate solvent gently along the vial wall. Swirl slowly until fully dissolved; avoid vigorous shaking.
- Reconstituted solution: Store at 2–8°C and use within the validated stability window; do not refreeze the solution.
- General: Handle with standard laboratory protective equipment (gloves, lab coat, eye protection).
Why Choose Our Thymalin?
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Verified Quality
Each batch tested by HPLC & MS; COA available upon request.
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Secure Packaging
Sealed vials with temperature-protective packaging for safe delivery.
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Fast Dispatch
Orders processed promptly with tracking provided.
Frequently Asked Questions
Q1: Is Thymalin the same as Thymosin Alpha-1 or Thymulin?
A: No. Thymalin is a thymus-derived peptide complex (a bioregulator containing multiple short peptides such as Glu-Trp and Lys-Glu). Thymosin Alpha-1 is a defined 28-amino-acid single peptide, and Thymulin is a zinc-binding nonapeptide — they are related but distinct thymic preparations.
Q2: How should I store it after receiving?
A: Keep unopened vials at -20°C for long-term storage. Once reconstituted, refrigerate at 2–8°C and use promptly; do not refreeze the solution.
Q3: Is a Certificate of Analysis (COA) available?
A: Yes, third-party tested COA documentation can be provided for each batch. Please contact our customer service with your order number.
⚠ Research Use Only — Disclaimer
All product information provided on this page is solely for information dissemination and educational purposes. The products offered are intended exclusively for in vitro laboratory research and are not pharmaceuticals. They have not been approved by the U.S. Food and Drug Administration (FDA) or any other regulatory authority for the purposes sold here, and must not be used to prevent, treat or cure any medical condition, disease or ailment.
It is strictly prohibited to introduce these products into the human or animal body in any form. By purchasing, the buyer acknowledges full responsibility for the proper handling, use and compliance with all applicable local laws and regulations.
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