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  • Adamax 5MG 10MG 20MG
  • Adamax 5MG 10MG 20MG
  • Adamax 5MG 10MG 20MG

Adamax 5MG 10MG 20MG

The peptide will be provided as lyophilized powder to ensure maximum stability.
Adamax is a cyclopentadienyl-substituted analog of Sema (Ac-MEHFPG-AG-Nh₂), combining structural features of both Sema and P21. As a synthetic neuropeptide biopharmaceutical, it mimics activity-dependent neuroprotective proteins by stabilizing microtubules and promoting the release of neurotrophic factors BDNF and NGF, thereby exerting multifaceted neuroprotection. Adamax enhances synaptic plasticity and improves learning/memory. In experimental treatments for neurodegenerative and developmental disorders like Alzheimer's disease and autism, it demonstrates potential for antioxidant and anti-inflammatory effects, reducing β-amyloid deposition, while also exhibiting endurance-enhancing and anxiolytic properties.
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  • Detail

    Adamax Research Peptide

    Semax-Related Nootropic & Neuroprotective Research Peptide

    Lyophilized Powder · For In-Vitro / Laboratory Research Use Only

    🧠 Semax-Lineage

    Derived from the ACTH(4-10) fragment family, the same backbone behind the well-studied nootropic peptide Semax.

    ⚗️ Modified Analog

    Structural modifications designed to improve stability and extend biological activity in experimental models.

    🔬 Nootropic Focus

    Investigated in cognitive, neuroprotective and synaptic-plasticity research workflows.

    🧊 High-Purity Powder

    Freeze-dried material with lot-specific COA; verify identity and purity before use.

    Product Overview

    Adamax is a synthetic research peptide belonging to the Semax lineage. Semax itself is a heptapeptide analog of the adrenocorticotropic hormone fragment ACTH(4-10), with the amino-acid sequence Met-Glu-His-Phe-Pro-Gly-Pro, long investigated for nootropic and neuroprotective activity. Adamax shares this backbone while carrying structural modifications that are explored for enhanced stability and more sustained biological activity in laboratory settings.

    Both compounds function as neuropeptides of research interest, studied for their influence on neurotransmitter systems, nerve-cell health and synaptic plasticity. Semax has a longer investigation history with published preclinical work, while Adamax remains in earlier stages of study. This makes Adamax a valuable comparative tool for researchers examining how structural variation within the ACTH(4-10) family affects neuroprotective and cognitive-related endpoints.

    Each vial contains 10mg of Adamax supplied as a lyophilized powder for in-vitro and laboratory research only.　

    Specifications

    Product Name Adamax
    Lineage / Class Semax-related modified peptide · ACTH(4-10) fragment family · Nootropic research peptide
    CAS Number 153931-84-9　
    Reference Parent (Semax) Sequence Met-Glu-His-Phe-Pro-Gly-Pro · Formula C₃₇H₅₁N₉O₁₀S · MW ≈ 813.9 g/mol · CAS 80714-61-0
    Adamax Exact Structure Modified analog — precise modification site, molecular formula, molecular weight and salt form must be confirmed from the batch-specific COA / analytical record.　
    Net Content 5mg/10mg/20mg
    Appearance White to off-white lyophilized powder
    Purity ≥ 99% (by HPLC, lot-specific)　
    Identity Confirmation LC-MS / mass confirmation recommended per batch　
    Storage Store at 2–8°C; for long-term storage, freeze and protect from light and moisture

    Relationship to Semax

    Adamax is best understood in the context of Semax, the better-characterized member of this peptide family. The table below compares what is established for Semax against the current status of Adamax, so researchers can set appropriate expectations.

    Aspect Semax (reference) Adamax
    Sequence Met-Glu-His-Phe-Pro-Gly-Pro (ACTH 4-10) Semax backbone with structural modification; exact site to confirm per batch
    Research History Extensive published preclinical literature Earlier-stage; fewer direct studies
    Design Goal Nootropic / neuroprotective ACTH fragment Improved stability & prolonged activity over Semax
    Status Research use only Research use only

    Research Areas of Interest

    🧠  Nootropic / cognitive research — studied within the ACTH(4-10) peptide family for influence on learning- and memory-related endpoints in experimental models.
    🛡  Neuroprotection research — the Semax lineage has been examined in focal-ischemia and neuronal-survival models; Adamax is explored as a comparative candidate.
    🔗  Synaptic plasticity — interest in neurotrophin-related signaling (e.g., BDNF/TrkB pathways documented for Semax) as a basis for further Adamax investigation.
    ⏱  Stability / structure-activity studies — how modifications to the Semax backbone influence persistence and activity in biological matrices.

    Note: BDNF/TrkB and neuroprotection findings above are documented primarily for Semax. They are provided as scientific background and should not be taken as confirmed Adamax effects; Adamax-specific endpoints must be established by direct testing of characterized material.

    Reconstitution & Handling

    💧  Perform a small-scale solubility test first with analytical-grade water or an assay-compatible buffer; record concentration, pH, appearance and recovery.
    🌀  Use gentle mixing only; avoid heating unless stability testing confirms it does not promote oxidation, breakdown or aggregation.
    🏷  Label each stock with batch number, solvent, concentration, preparation date and storage condition; set use periods based on stability assessment.
    🧊  Where supported by stability data, aliquot into single-use portions to reduce repeated freeze-thaw cycles.　

    Quality Assurance

    ✔  Lot-specific Certificate of Analysis: HPLC purity confirmation + mass-spectrometry identity verification.　

    ✔  Because Adamax's exact structure is not fully standardized across suppliers, we recommend confirming the batch COA — including structure/sequence, salt form and theoretical mass — before use.

    ✔  Third-party batch testing documentation available upon request.　

    References & Further Reading

    1. Dolotov OV, et al. Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain Research. 2006;1117(1):54-60.
    2. Dolotov OV, et al. Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain. J Neurochem. 2006;97(Suppl 1):82-86.
    3. Dmitrieva VG, et al. Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia. Cell Mol Neurobiol. 2010;30(1):71-79.
    4. Medvedeva EV, et al. The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia. BMC Genomics. 2014;15:228.
    5. Semax — Wikipedia / PubChem CID 9811102 (sequence, formula, molecular weight reference).
    Disclaimer: This product is an experimental research compound intended exclusively for in-vitro laboratory research use. It is not approved for human or animal use, is not a drug, food, cosmetic, or dietary supplement, and is not intended to diagnose, treat, cure or prevent any disease. Adamax is in early stages of investigation; structure, purity and properties must be confirmed via the batch-specific Certificate of Analysis. All products are supplied strictly for research purposes only.
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